منابع مشابه
Gastrointestinal complications induced by sevelamer crystals
BACKGROUND Sevelamer is a phosphate binder widely used in chronic kidney disease (CKD) patients. Sevelamer, as well as other resin-based binders, can crystallize leading to the formation of concretions. Sevelamer crystals (SC) have been associated with gastrointestinal (GI) mucosal injury. We describe three new cases of GI lesions associated with SC and review previously reported cases. METHO...
متن کاملSevelamer-Induced Gastrointestinal Injury Presenting as Gastroenteritis
End-stage renal disease (ESRD) is a common disease encountered in clinical practice and is associated with increasing metabolic derangements through disease progression. Phosphate retention is one of the most common derangements and is associated with increased mortality. Hyperphosphatemia becomes increasingly prevalent as glomerular filtration rate decreases. Non-calcium phosphate-binding resi...
متن کاملPeritoneal dialysis patients using sevelamer do not present the acidosis problems that hemodialysis patients do.
Acidosis is responsible for catabolic state in dialysis patients and should be avoided or corrected. The survival of patients on peritoneal dialysis (PD) is as good as that of patients on hemodialysis--if not better-mainly because PD patients are rarely in an acidotic-catabolic state as compared with hemodialysis patients. We investigated whether the use of sevelamer in PD patients contributes ...
متن کاملPhosphate Binding with Sevelamer Preserves Mechanical Competence of Bone Despite Acidosis in Advanced Experimental Renal Insufficiency
INTRODUCTION Phosphate binding with sevelamer can ameliorate detrimental histomorphometric changes of bone in chronic renal insufficiency (CRI). Here we explored the effects of sevelamer-HCl treatment on bone strength and structure in experimental CRI. METHODS Forty-eight 8-week-old rats were assigned to surgical 5/6 nephrectomy (CRI) or renal decapsulation (Sham). After 14 weeks of disease p...
متن کاملCorrection of metabolic acidosis after conversion from sevelamer hydrochloride to lanthanum carbonate
Correction of metabolic acidosis after conversion from sevelamer hydrochloride to lanthanum carbonate Sir, We recently introduced lanthanum carbonate as an alternative phosphate binder to sevelamer hydrochloride in patients with elevated serum calcium. Lanthanum carbonate has a higher affinity for phosphate than sevelamer HCl, so fewer lanthanum carbonate tablets are required to achieve the sam...
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ژورنال
عنوان ژورنال: Kidney International
سال: 2005
ISSN: 0085-2538
DOI: 10.1111/j.1523-1755.2005.67142_2.x